Laser Assisted Hatching

Laser Assisted hatching is a technique used in In-Vitro Fertilisation (IVF) that may
improve the implantation of embryos into a woman’s uterine lining by
creating an opening through which the embryonic cells can hatch out. Pregnancy cannot
occur unless the embryo hatches.

What is Infertility?

Infertility is a condition of not getting pregnant, despite having regular unprotected intercourse for a year or
more. To determine whether a couple is Infertile or not, the doctor examines their health history, medications,
and sexual history. In about 80 % of the couples, the cause of infertility is either an ovulation problem,
blockage of fallopian tubes, or a sperm problem.

LAH is used in patients with poor prognosis to help with the implantation of the embryo. The embryo in its early stage stays within a membrane that is known as Zona Pellucida. The embryo must first break through the zona pellucida to implant successfully in the uterine lining. In Assisted hatching, an embryologist does the same. He uses micromanipulation techniques under a microscope and makes a small hole in the zona pellucida, which helps the embryo to implant in the uterine lining. Some embryos seem to have a thicker shell that may diminish their ability to hatch and reduce the likelihood that they will implant. This may be due to the age of the woman or other unknown reasons.

Hatching of the embryo is necessary to achieve pregnancy. It has been reported that up to 75% of normal embryos may never hatch. Laboratory procedures involved in IVF may add to the hardening of the zona, as the embryo is not continually exposed to the enzymes present in the natural environment of the Fallopian tubes. There is also evidence to suggest that the process of freezing and thawing embryos may cause the zona to harden and using assisted hatching can be beneficial.

Female Fertility

When the cause of infertility exists within the female partner which does not let her conceive over the course of a year, then it is referred to as Female Infertility. The most common causes leading to infertility in women include problem with ovulation, damaged blocked fallopian tube, damaged or abnormal uterus shape or problem with the cervix. Higher age can also cause fertility problems in a woman, because as a woman ages, her fertility quotient tends to decrease.

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Male Fertility

Male Infertility is a reproductive health issue in a man that lowers the chances of his female partner getting pregnant and accounts for 3035% of infertility cases. Male infertility is normally caused by problems that affect either the sperm production, the sperm transport, sperm quality and can be evaluated by a detailed semen analysis report that may show a sperm count, sperm motility or a problem related to sperm morphology(shape).

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IVF with Donor Embryos

IVF with donor embryos may be recommended in cases where both male and female partners having fertility issue. The female's eggs and the male's sperm are not capable of achieving a healthy pregnancy. In donor Embryo IVF both the gametes(eggs and sperms) are taken from anonymous donor and resultant embryos are transferred to the female partners uterus.This solution can also be recommended when there's a chance that the embryo can inherit a genetic problem from the male or female partner.

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Fertility Preservation

Fertility preservation is the preservation of the eggs and/or sperm for use at later date. The process enables the preservation of eggs or sperm before the female or male starts a medical treatment that could have a negative impact on their eggs or sperm, such as cancer treatment.

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