AMH or Anti-Müllerian Hormone is an indicator of ovarian reserve in women. It is secreted by the Granulosa cells of the antral follicles, and then it is released in the follicular fluid and blood vessels. Follicles are the sacs which contain the immature eggs. Low AMH is an indicator of low ovarian reserve. A blood test is done to check for the AMH value, which gives us an insight of ovarian responsiveness that is how many eggs are left in the ovaries. The AMH value will help to determine how urgently a woman needs to seek treatment and how she will respond to it.
AMH decreases with age because as a woman ages, her ovarian reserve gets depleted as well. And depleted ovarian reserve might lead to fertility issues. Critically low values would also indicate a reduced response to ART. So, during preliminary investigations, if a woman’s AMH value is found to be low, she must consider getting treatment without further delay.
Low AMH means that the woman’s ovarian reserve is rapidly declining, and she should seek fertility treatment immediately if she’s trying to have a baby.
The reference range for AMH value should be within 2.20 – 6.80 ng/mL. The range can vary from laboratory to laboratory depending on the types of equipment and testing methods. However, the age of the patient plays a significant role in predicting the outcome as low AMH always do not predict low ART success in women under 35 years of age. Also, other laboratory parameters like imaging techniques and clinical findings should be considered.
Low AMH level is not the cause of infertility, and it only indicates that there is a low ovarian reserve. That means that the number of eggs developing in the ovaries are limited, and the chance of a mature good quality egg releasing every month and getting fertilised decreases. Also, with age, the quality of eggs gets affected. So, the chances of early miscarriages due to abnormalities in the egg increases. Early pregnancy losses account for 85%.
There are no specific low AMH symptoms that suggest that a woman may have a low AMH. But if a woman has irregular periods or has premature menopause, then she can get herself tested for AMH through a blood test.
AMH level is determined by the number of follicles that develop in the ovaries. But while considering the reason for low AMH levels, the age of the woman plays a significant role. Ovarian reserve tends to decline when a woman is in her mid-30’s and becomes even lower in a woman who is 40 years and above.
Some of the points on what causes Low AMH include:
There is no low AMH treatment, but there are ways through which a woman can improve her AMH before considering ART as an option, so that quantity and quality of eggs improve before IVF treatment.
The natural low AMH fertility treatment options to improve AMH values may be suggested so that it might increase the ovarian response during stimulation.
Some of the low AMH natural treatments are:
Some other Low AMH fertility treatment options for conceiving a baby include:
AMH (Anti Mullerian Hormone) has been suggested as a marker of the quantity of the oocytes remaining in the ovaries. Having low AMH is a sign of the declining ovarian reserve, it cannot be transformed to high amh levels. It simply means that low amh and natural pregnancy does not usually go even , so if you are planning a pregnancy and once diagnosed with Low AMH, a fertility expert should be immediately consulted.
Medicover Fertility has successfully helped many women with many infertility issues, including Low AMH, to conceive a pregnancy and become parents.
In case of planning a pregnancy with Low AMH, consult our fertility expert by calling us at +917862800700.
Yes! A low AMH can cause miscarriage because with low AMH the chances of a good quality egg releasing and getting fertilised diminishes. And with poor quality egg, the chances of early miscarriages due to abnormalities in the egg increases.
There may be effects on the ovary due to endometriosis, and ovarian endometriomas can directly affect the ovarian reserve, thus causing low AMH levels.
Low AMH is not the exact cause of infertility, but it is an indicator of ovarian reserve. Depleted ovarian reserve can lead to problems affecting pregnancy and infertility if there are lesser number of eggs or no eggs in ovarian reserve, the chance of getting pregnant decreases.
A low AMH and high FSH would mean that both the quality and quantity of eggs formed are not good.